We are conducting a study to examine the effects of weight loss on 11-oxyandrogens in women with and without polycystic ovary syndrome (PCOS). The 11-oxyandrogens are a recently discovered group of hormones with similar effects to the male hormone, testosterone. Evidence suggests that 11-oxyandrogens may contribute to the symptoms of PCOS. The aim of this study is to determine the importance of 11-oxyandrogens to the development of PCOS, and their relationship with body mass index (BMI) and insulin resistance.
We are recruiting women aged 18 to 45 years:
- who have decided to undergo bariatric surgery or,
- have PCOS symptoms including acne, hirsutism, female pattern hair loss or irregular menstrual cycles.
We are also inviting participation from healthy women with regular menstrual cycles and no PCOS symptoms, to allow comparison.
What does participation involve?
Participation will involve a clinical assessment by Dr Jennifer Ng, Endocrinologist, and a fasting blood test. For participants undergoing weight loss surgery, clinical assessments and blood tests will be performed pre-operatively and at 3 and 6 months post-operatively
Contacts
If you are interested in participating, or for further information please email Jennifer.ng@research.uwa.edu.au
For surgeons or clinicians with suitable patients please refer here..
